powershell

Download reference: https://gist.github.com/HarmJ0y/bb48307ffa663256e239

Base64 encode

[Convert]::ToBase64String((Get-Content -path "C:\Windows\system32\drivers\etc\hosts" -Encoding byte))

Calculate MD5 hash

Get-FileHash "C:\Windows\system32\drivers\etc\hosts" -Algorithm MD5 | select Hash